CRP (C-Reactive Protein) Test

C-Reactive Protein (CRP) is a protein produced by the liver in response to inflammation, infection, or tissue damage.

What does the CRP test measure?

The CRP test measures the level of CRP in the blood, indicating the presence and severity of inflammation.

Purpose of CRP test:

1. Diagnose infections (bacterial, viral, or fungal)

2. Monitor inflammation (e.g., arthritis, vasculitis)

3. Assess risk of cardiovascular disease

4. Monitor cancer treatment response

5. Detect autoimmune disorders (e.g., rheumatoid arthritis)

Types of CRP tests:

1. Standard CRP (sCRP)

2. High-sensitivity CRP (hs-CRP) - more sensitive for cardiovascular risk assessment

Interpretation of results:

Normal range: 0-10 mg/L (varies by lab)

Elevated levels:

- Mild elevation (10-50 mg/L): minor inflammation or infection

- Moderate elevation (50-100 mg/L): significant inflammation or infection

- High elevation (>100 mg/L): severe inflammation, infection, or sepsis

Limitations:

1. Non-specific (elevated in various conditions)

2. May not distinguish between acute and chronic inflammation

When is the CRP test ordered?

1. Symptoms of infection (fever, pain, swelling)

2. Inflammatory conditions (arthritis, asthma)

3. Cardiovascular risk assessment

4. Monitoring chronic conditions (diabetes, cancer)

5. Pre-operative evaluation

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