𝐂𝐞𝐧𝐭𝐫𝐢𝐟𝐮𝐠𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐁𝐥𝐨𝐨𝐝 𝐂𝐨𝐦𝐩𝐨𝐧𝐞𝐧𝐭𝐬⁣

Centrifugation is a laboratory technique used to separate the components of whole blood based on their density by spinning the sample at high speed. When whole blood is placed in a centrifuge, its components form distinct layers:⁣

⁣

𝟏. 𝐏𝐥𝐚𝐬𝐦𝐚 𝐚𝐧𝐝 𝐏𝐥𝐚𝐭𝐞𝐥𝐞𝐭𝐬 (𝐓𝐨𝐩 𝐋𝐚𝐲𝐞𝐫 – 𝟓𝟓%)⁣

Colour: Pale yellow⁣

Composition: Water, proteins, hormones, nutrients, waste products⁣

Platelets: Small cell fragments involved in blood clotting⁣

Reason for position: Least dense, so they rise to the top⁣

⁣

𝟐. 𝐖𝐡𝐢𝐭𝐞 𝐁𝐥𝐨𝐨𝐝 𝐂𝐞𝐥𝐥𝐬 (𝐌𝐢𝐝𝐝𝐥𝐞 𝐋𝐚𝐲𝐞𝐫 – 𝐁𝐮𝐟𝐟𝐲 𝐂𝐨𝐚𝐭)⁣

Colour: Thin whitish layer⁣

Composition: Leukocytes (neutrophils, lymphocytes, monocytes, eosinophils, basophils)⁣

Function: Defence and immunity⁣

Reason for position: Intermediate density⁣

⁣

𝟑. 𝐑𝐞𝐝 𝐁𝐥𝐨𝐨𝐝 𝐂𝐞𝐥𝐥𝐬 (𝐁𝐨𝐭𝐭𝐨𝐦 𝐋𝐚𝐲𝐞𝐫 – 𝟒𝟓%)⁣

Colour: Red⁣

Function: Transport oxygen and carbon dioxide⁣

Reason for position: Most dense, so they settle at the bottom⁣.

 *Why Centrifugation is Important?⁣* 

- Helps isolate plasma for diagnostic tests⁣

- Separates RBCs for transfusion⁣

- Allows examination of specific blood components⁣

- Essential for haematology and clinical laboratory procedures⁣

#Clinic #biochemistry #hematology #biology