𝐀𝐂𝐄 𝐓𝐞𝐬𝐭 (𝐀𝐧𝐠𝐢𝐨𝐭𝐞𝐧𝐬𝐢𝐧 𝐂𝐨𝐧𝐯𝐞𝐫𝐭𝐢𝐧𝐠 𝐄𝐧𝐳𝐲𝐦𝐞 𝐓𝐞𝐬𝐭)

The ACE test is a biochemical blood test used to measure the level of Angiotensin Converting Enzyme (ACE) in serum.

🔹 Why is ACE Test done?

This test is mainly done to help in the diagnosis and monitoring of Sarcoidosis, a granulomatous disease. It is also useful to check disease activity and response to treatment.

🔹 Sample Required:
🩸 Serum

🔹 Principle:

ACE enzyme present in the patient’s serum acts on a synthetic substrate and converts it into a product.
The amount of product formed is directly proportional to the ACE level in the blood.

🔹 Normal Values:

• Adults: 8 – 52 U/L
(Normal range may vary from lab to lab)

🔹 Increased ACE Levels seen in:
• Sarcoidosis
• Tuberculosis
• Leprosy
• Liver diseases
• Diabetes mellitus

🔹 Decreased ACE Levels seen in:
• Patients taking ACE inhibitor drugs
• Chronic lung diseases

🔹 Clinical Importance:

ACE test is very helpful in monitoring the progression and treatment response of Sarcoidosis.
It is not a confirmatory test alone but supports clinical findings.