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Scientists discover Alzheimer’s hidden “death switch” in the brain

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A team led by neurobiologist Prof. Dr. Hilmar Bading at Heidelberg University has identified a key molecular process that drives the progression of Alzheimer's disease. Working with researchers from Shandong University (China), the scientists used a mouse model of Alzheimer's to show that a harmful protein interaction causes brain cells to die, leading to cognitive decline. The findings point to new possibilities for developing more effective treatments. The harmful protein interaction involves two components previously studied: the NMDA receptor and the TRPM4 ion channel. NMDA receptors play an essential role in communication between nerve cells and are located on the cell surface, both at synapses and in areas outside these junctions. They are activated by glutamate, a key neurotransmitter. When NMDA receptors function within synapses, they support neuron survival and help maintain cognitive function. However, when TRPM4 interacts with NMDA receptors outside synap...
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Professor Yemi Osinbajo

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Oluyemi "Yemi" Oluleke Osinbajo (born 8 March 1957) is the Vice President of Nigeria, in office since 29 May 2015. He is also a Senior Advocate of Nigeria, Professor of Law and until his inauguration as Vice President, a Senior Partner with SimmonsCooper Partners, a commercial law practice. Marriage, family and personal life Yemi Osinbajo was born into the family of Opeoluwa Osinbajo on 8 March 1957, Creek Hospital, Lagos. Osinbajo is married to Dolapo (née Soyode) Osinbajo, a granddaughter of Obafemi Awolowo. They have three children together. Education Yemi Osinbajo was educated at Corona primary School, in Lagos. Between 1969–1975, he attended Igbobi College Yaba, Lagos, Nigeria. From 1975–1978, he studied for his undergraduate degree in Law at the University of Lagos, where he was awarded a LLB Law degree. From 1979–1980 he attended Nigerian Law School. In 1981, he was awarded a Master of Laws after attending the London School of Economics. Legal career ...
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FG declares Monday as public holiday

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The Federal Government of Nigeria has through the Ministry of Interior declared Monday 13th of June, 2022, as a public holiday to mark the 2022 Democracy day. The Minister of Interior, Ogbeni Rauf Aregbesola, made this known in a statement signed by the Permanent Secretary of the Ministry, Dr M. L. Shuaib Belgore, on Thursday. He congratulated Nigerians and urged all citizens to support the present administration in its efforts at ensuring a secured, united and prosperous nation. Aregbesola admonished Nigerians to use the occasion to reflect on the long journey the country has made towards the enthronement of civil democratic order, before Independence in 1960 till date and the sacrifices of our patriots. “As we mark another Democracy Day in the history of our dear country, let us reflect on the efforts of our founding fathers and ensure that Nigeria remains one united, secured, peaceful and an indivisible entity, noting that no development can take place in an acrimonious environment....
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Chief Ebola Doctor Contracts Ebola

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A doctor who has played a key role in fighting the Ebola outbreak in Sierra Leone is infected with the disease, according to that country's Ministry of Health. Dr: Shelk Humarr Khan is being treated by the French aid group Medecins Sans Frontieres - also known as Doctors Without Borders - in Kailahum, Sirra Leone, Tim Shenk, an agency spokesman, told CNN. Until falling ill, Khan had been overseeing Ebola treatment and isolation units at Kenema Government Hospital, about 185 miles east of the capital Freetown. Citing patient confidentiality, Shenk declined to provide additional details about Khan's condition.The Ministry of Health took to Facebook to deny reports te doctor had died. The minisry "wishes the general public and all partners working in the healthcare sector to know that, ...Khan is still alive and responding to treatment comtrary to social media report of his demise," according to a Facebok post. Sierra Leone has had 427 confirmed cases of Ebola and 144 ...
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Five naira note

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Dimensions 130mm x 72mm Date Released 28th February, 2007 Design: Predominant Colour: Mauve The N5 note was originally introduced in 1979 and in 1984 the colours were changed while the essential features of the note remained the same. The main feature on the front is the engraved portrait of Alhaji Sir Abubarkar Tafawa Balewa (1912-1966), educationist, and the first Prime Minister from September 1957 to January1966. The back illustrates Nkpokiti Dancers from the South Eastern part of  Nigeria Alhaji Sir Abubakar Tafawa Balewa (1912-1966) Sir Abubakar Tafawa Balewa, the first Prime Minister of of independent Nigeria (1960-1966) was born in Tafawa Balewa, a town in Bauchi State, and was educated as a teacher. He later became a politician, and was elected to the Northern Region's House of Assembly in 1947, and in 1951, to the Federal House of Representatives. He was a founder and until his death, the deputy president of the Northern People's Congress. Balewa became Prim...
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Kenya coins replace leaders with animals

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copyright KENYA CENTRAL BANK Kenya has dropped the images of presidents from newly minted cash coins, in what is seen as an attempt to prevent their glorification. Previous coins bore the images of Kenya's three ex-rulers: Jomo Kenyatta, Daniel arap Moi and Mwai Kibaki. Many Kenyans saw this as an attempt by their leaders to promote themselves, and to personalise the state. The new ones have images of the country's famous wildlife, including lions, elephants, giraffes and rhinos. President Uhuru Kenyatta - the son of Kenya's first leader Jomo Kenyatta - said the new coins were a "big change" and showed "our nation has come a long way". All three of the incumbent's predecessors had their images printed on the currency during their rule. Mr Kibaki, who won elections in 2002 ending Mr Moi's 24-year rule, broke a promise not to have his image printed on money. copyrightGETTY IMAGES Notes with images of Kenya's founding leader Jomo Ken...
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Sickle Cell Test

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1. Objective The objective of the Sickle Cell Test was to detect the presence of Hemoglobin S (HbS), which caused sickle cell disease or sickle cell trait. The test aimed to screen or diagnose individuals who inherited the mutated beta-globin gene. 2. Principle The principle of the test was based on the fact that Hemoglobin S polymerized under low oxygen tension, causing red blood cells to become crescent or sickle-shaped. These abnormally shaped cells were detected microscopically (sickling test), through solubility tests, or by electrophoresis to differentiate hemoglobin types. 3. Materials • Anticoagulated blood sample (EDTA) • Sodium metabisulfite (for sickling test) • Microscope and glass slides • Hemoglobin electrophoresis equipment (for confirmatory test) • Solubility test reagent kit (for rapid screening) • Coverslips • Test tubes and pipettes • Gloves and safety equipment 4. Procedure (Microscopic Sickling Test) 1. A drop of the patient’s blood was placed on a clea...
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